Scientific References

AUTHORS : Meloni M

MODELS : HVE / HUMAN VAGINAL EPITHELIUM

APPLICATIONS : Medical device

Demonstrating the principal mechanism of action of medical devices intended for vaginal use on reconstructed human vaginal epithelium: the case of two hyaluronic acid-containing devices

2024 Frontiers in Drug Safety and Regulation | VitroScreen, In Vitro Research Laboratory, Milan, Italy - Biocodex SA, Centre de R&D, Compiègne, France - Department of Obstetrics and Gynecology, Montpellier University Hospital, Montpellier, France Regulation

AUTHORS : Carlomagno Federica Meloni M

MODELS : HVE / HUMAN VAGINAL EPITHELIUM

APPLICATIONS : PHARMACOLOGY / TOXICOLOGY SKIN METABOLISM SKIN SENSITIZATION

Evaluation of Antimicrobial, Antiadhesive and Co-Aggregation Activity of a Multi-Strain Probiotic Composition against Different Urogenital Pathogens

2023 International Journal o f Molecular Sciences | SynBalance srl, Origgio, VA, Italy - VitroScreen srl, Milan, MI, Italy - Complife Italia srl, Garbagnate Milanese, MI, Italy - Roelmi HPC srl, Origgio, VA, Italy

AUTHORS : Ceriotti L Craviotto V Damico F Lamonaca L Meloni M Pellegatta G Spadaccini M

MODELS : HEE / HUMAN ESOPHAGEAL EPITHELIUM

APPLICATIONS : Permeability

Evaluation of Human Esophageal Epithelium Permeability in Presence of Different Formulations Containing Hyaluronic Acid and Chondroitin Sulphate

2020 Medical Devices: Evidence and Research | VitroScreen, Milano, Italy - Humanitas Clinical and Research Center and Humanitas University, Digestive Endoscopy Unit, Division of Gastroenterology, Rozzano, MI, Italy

AUTHORS : Alonso B Centeno A Fusco L Garrido M Martin C Pelin M Ponti C Prato M Sosa S Tubaro A Vazquez E Zurutuza A

MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS

APPLICATIONS : Skin irritation SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS

Skin irritation potential of graphene-based materials using a non-animal test

2020 Nanoscale | a Department of Chemical and Pharmaceutical Sciences, University of Trieste, Via Giorgieri 1, 34127 Trieste, Italy. E-mail: [email protected], [email protected] b Instituto Regional de Investigación Científica Aplicada (IRICA), 13071 Ciudad Real, Spain. E-mail: [email protected] c Departamento de Química Orgánica, Facultad de Ciencias y Tecnologías Químicas, Universidad de Castilla-La Mancha (UCLM), 7 13071 Ciudad Real, Spain. E-mail: [email protected] d Department of Life Sciences, University of Trieste, Via Valerio 6, 34127 Trieste, Italy. E-mail: [email protected], [email protected], [email protected], [email protected]; Tel: +3904055888620 e Graphenea, Paseo Mikeletegi 83, Donostia-San Sebastián, 20009, Spain. E-mail: [email protected], [email protected], [email protected] f Carbon Nanobiotechnology Laboratory CIC BiomaGUNE, Paseo de Miramón 182, Donostia-San Sebastián, 20009, Spain. E-mail: [email protected] g Basque Foundation for Science (IKERBASQUE), Bilbao, 48013, Spain

AUTHORS : Arbey E Cubberley R Duplan H Eilstein Joan Ellison C Fabre A Genies C Gregoire S. Hewitt NJ Jacques-Jamin C Klaric M Lange D Rothe H Schepky A

MODELS : EPISKIN

APPLICATIONS : SKIN METABOLISM

Comparison of the metabolism of 10 cosmetics-relevant chemicals in EpiSkin™ S9 subcellular fractions and in vitro human skin explants

2019 Journal of Applied Toxicology | 1 Pierre Fabre Dermo-Cosmétique, Toulouse, France - 2 Coty, Darmstadt, Germany - 3 The Procter & Gamble Company, Ohio, Cincinnati, USA - 4 Unilever, Sharnbrook, UK - 5 Beiersdorf AG, Hamburg, Germany - 6 Cosmetics Europe, Brussels, Belgium - 7 L'Oreal, Aulnay-Sous-Bois, France

AUTHORS : Branco J Lisboa C Mendes CS Miranda IM Pedrosa A Pellevoisin C Rodrigues AG

MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS

APPLICATIONS : SKIN METABOLISM

Malassezia clinical isolates behavior on a reconstructed human epidermis

2019 Micoses, 2019 Oct;62(10):932-936. doi: 10.1111/myc.12965. Epub 2019 Jul 29. | University of Porto, Porto, Portugal, Centro Hospitalar S.João EPE, Porto, Portugal, Center for Health Technology and Services Research, University of Porto, Porto, Portugal, Episkin Academy, Lyon, France, Cardiovascular R&D Centre, Faculty of Medicine, University of Porto, Porto, Portugal 6 Burn Unit, Department of Plastic and Reconstructive Surgery, Centro Hospitalar S.João EPE, Porto, Portugal

AUTHORS : Baillet-Guffroy A El Khoury R Lteif R Michael-Jubeli R Salameh D Tfayli A Zeitoun H

MODELS : RHPE / RECONSTRUCTED HUMAN PIGMENTED EPIDERMIS

APPLICATIONS : Depigmentation

Skin lightening effect of natural extracts coming from Senegal botanical biodiversity

2019 International Journal of Dermatology | 1 Unite de Technologie et Valorisation Alimentaire, Centre d’Analyses et de Recherche, Universite Saint-Joseph, Beirut, Lebanon, and 2 Interdisciplinary Unit: Lipids, Analytical and Biological Systems Lip(Sys)2 , Faculty of Pharmacy, Univ Paris-sud, Universite Paris-Saclay, Chatenay-Malabry, France

AUTHORS :

MODELS : HGE / HUMAN GINGIVAL EPITHELIUM

APPLICATIONS : PERCUTANEOUS ABSORPTION Skin irritation SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS

Biofilm-stimulated epithelium modulates the inflammatory responses in co-cultured immune cells

2019 Nature | Institute of Biomedical and Environmental Health Research, School of Science and Sport, University of the West of Scotland, Paisley, UK - Oral Sciences Research Group, Glasgow Dental School, School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK - Department of Life Sciences, School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, UK - Oral Healthcare R&D, GlaxoSmithKline Consumer Healthcare, Weybridge, UK

AUTHORS :

MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS

APPLICATIONS : Anti-Aging DNA Damage SKIN METABOLISM

An in vitro model to evaluate the impact of environmental fine particles on skin damage

2019 Elsevier - Toxicology Letters 305 (2019) 94-102 | Unité de Chimie Environnementale et Interactions sur le Vivant EA4492, SFR Condorcet FR CNRS 3417, Université du Littoral Côte d’Opale, 59140, Dunkerque, France; Centre Commun de Mesures (CCM), Université du Littoral Côte d’Opale, 59140, Dunkerque, France; Laboratoires Clarins, 95300, Pontoise, France; INSERM UMR 1153 - CRESS, HERA (Health Environmental Risk Assessment) Research Unit, Paris Descartes-Sorbonne Paris Cité University, Paris, France; AP-HP Hôpital Bichat, Laboratoire de Biochimie, 75018, Paris, France

AUTHORS : Adriaens E. Alepee N. McNamee P Pfannenbecker U

MODELS : HCE / HUMAN CORNEAL EPITHELIUM

APPLICATIONS : Eye irritation

Development of a defined approach for eye irritation or serious eye damage for liquids

2019 Elsevier - Toxicology In vitro 57 (2019) 154-163 | L'Oréal Research & Innovation, Aulnay Sous Bois, France; Adriaens Consulting, Aalter, Belgium; Kao Corporation, Safety Science Research, Kanagawa, Japan; D. Bagley, Colgate-Palmolive Co., Piscataway, NJ, USA; Cosmetics Europe - The Personal Care Association, Brussels, Belgium; Chanel Parfums Beauté, Neuilly sur Seine, France; Henkel AG & Co. KGaA, Düsseldorf, Germany; Beiersdorf AG, Hamburg, Germany; Kao Corporation, S.A., Barcelona, Spain; HP Inc., Barcelona, Spain; VITO NV (Flemish Institute for Technological Research), Mol, Belgium l The Procter & Gamble Company, Egham, United Kingdom

AUTHORS : Adriaens E. Alepee N. McNamee P Pfannenbecker U

MODELS : HCE / HUMAN CORNEAL EPITHELIUM

APPLICATIONS : Eye irritation OCULAR IRRITATION OF CHEMICAL

Development of a defined approach for eye irritation or serious eye damage for neat liquids

2019 Toxicology in Vitro | L'Oréal Research & Innovation, Aulnay Sous Bois, France b Adriaens Consulting, Aalter, Belgium c Kao Corporation, Safety Science Research, Kanagawa, Japan d Colgate-Palmolive Co., Piscataway, NJ, USA e Cosmetics Europe - The Personal Care Association, Brussels, Belgium f Chanel Parfums Beauté, Neuilly sur Seine, France g Henkel AG & Co. KGaA, Düsseldorf, Germany h Beiersdorf AG, Hamburg, Germany i Kao Corporation, S.A., Barcelona, Spain j HP Inc., Barcelona, Spain k VITO NV (Flemish Institute for Technological Research), Mol,

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