T-Skin / Human Full Thickness Model

Name

T-Skin^TM / Reconstructed Human Full Thickness Skin Model

Description

T-Skin^TM is an in vitro reconstructed skin which consists of a dermal equivalent with human fibroblasts overlaid by a stratified, well differentiated epidermis derived from normal human keratinocytes cultured on an inert polycarbonate filter.

This model exists at different stages of maturity.

Specific markers

Differentiation markers:

Filaggrin (See picture)
Involucrin
Loricrin
Cytokeratin 10 (See picture)
Transglutaminase-1 (See picture)

Dermal-Epidermal junction markers

Collagen IV, VII, XII (See picture)
Laminin V (See picture)
Perlecan (See picture)
BP antigen

Proliferation markers

Ki67 (See picture)

Applications

UV Exposure
DNA Damage
Bacterial adhesion
Omics
Permeability

Format

6 well plate (See picture)