SkinEthic RHE / Human Epidermis


SkinEthicTM RHE / Reconstructed Human Epidermis


SkinEthicTM RHE is an in vitro reconstructed human epidermis from normal human keratinocytes cultured on an inert polycarbonate filter at the air-liquid interface. It is histologically similar to the in vivo human epidermis. 

Our strong believe in Science and our continuous improvement with ISO 9001 certification push us to keep improving the production process of our model: From cell extraction to reconstruction with chemically defined biocomponents and medium.

Every single biocomponent of each step of our production is clearly defined and their traceability is guaranteed. The process is then more secured, allowing to deliver a SkinEthicTM RHE model more reproducible, robust and reliable than ever. 

Different maturities and surfaces are available. 


Specific markers

Differentiation markers:

Dermal-Epidermal junction markers

  • Type IV collagen
  • Laminin V (See picture)
  • Alpha6Beta4-integrin
  • BP antigen

Proliferation markers

RHE in Vitro
in vitro



Cell Migration Model

Cell Migration Model


Cell Migration Models (CMM) are epidermal models on an innovative insert.


Epidermal or mucosal reconstructed on this insert are histologically similar to in vivo human epidermis and mucosa.