SkinEthic HCE validated by OECD for 492B test method

OECD Validation Time to Toxicity method on SkinEthic HCE


SkinEthic™ HCE TIME-TO-TOXICITY is the first stand alone method validated by the OECD (June 30, 2022) for discriminating on its own the three UN GHS Ocular Hazard categories.


This SkinEthic™ Human Corneal Epithelium (HCE) Time-to-Toxicity (SkinEthic HCE TTT) is an in vitro procedure allowing the identification on its own of chemicals (substances and mixtures) not requiring classification (No Cat), labelling for eye irritation (Cat 2) and serious eye damage (Cat 1) in accordance with the three UN GHS ocular hazard categories.


You can access The SkinEthic™ HCE Time-to-Toxicity in vitro test method on Liquids (SkinEthic™ HCE TTL) and on Solids (SkinEthic™ HCE TTS) by checking our Eye Irritation page on our website or reading it on OECD website: