EPISKIN will welcome you at #WC13 2025 Congress in Rio de Janeiro, Brazil, from August 31 to September 4, 2025!
The World Congress (WC) on Alternatives and Animal Use in the Life Sciences is considered as one of the most important scientific meetings of the year in the toxicological field. WC brings together, every three years, more than 800 scientists from different industries, regulatory authorities, NGOs, academia all around the world.
Starting with the first edition in 1993, it is the most important event in the promotion and development of non-animal testing methods.
For over 40 years, L'Oréal has pioneered alternative methods for cosmetics with no animal testing and has been a major sponsor of this congress since 2005.
L'Oréal is proud to be the Diamond Sponsor of the #WC13 2025 Congress!
But this year, we want to go further
1️⃣ L'Oréal Innovation Village: For the first time, we're offering booth space within the L'Oréal Innovation Village to 5 innovative startups contributing to the development of New Alternative Methods (NAMs)
2️⃣ L’Oréal Travel Grants: L'Oréal is sponsoring 6 travel grants to support early-career researchers passionate about non-animal testing methods
Discover the future of beauty innovation at the L'Oréal Innovation Village! Engage directly with our experts and be among the first to learn about our cutting-edge advancements.
Our complete scientific program features dynamic conferences and presentations on our latest news and research, 8 posters presentation:
POSTER 109
In vitro injury model using reconstructed human epidermis at different maturation stages
Animal Health – Replacement
Thais Canuto Pereira 1, Ronaldo José Farias Corrêa do Amaral 2, Vanja Dakic 3
1 Episkin Brazil Biotechnology/Federal University of Rio de Janeiro
2 Federal University of Rio de Janeiro
3 Episkin Brazil Biotechnology
POSTER 357
Adipose Tissue Organoids Modulate Epidermal Regeneration in a 3D Co-culture Model
Human Health – Reduction
Taisnara Ingrid Gonçalves Silva 1, Tathiana Proença Pampolha 1, Érica Almeida Amorim 1, Vanja Dakic 2, Leandra Santos Baptista 3
1 1 Gcell 3D, Rio de Janeiro, Brazil
2 2 L'Oréal Research and Innovation, Rio de Janeiro, Brazil; 3 Episkin Brasil Biotecnologia, Rio de Janeiro, Brazil
3 4 Multidisciplinary Research Center (Numpex-Bio), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
POSTER 128
Wound healing assay to evaluate corneal damage reversibility in SkinEthic HCE Model
Human Health – Replacement
Martina Daniela Benedetti 1, Mariela Lenze 1, Mora Renée García 1, Marcela Sofía Sosa 2, Vanja Dakic 3, María Laura Gutierrez 1
1 CONICET (Consejo Nacional de Investigaciones Científicas y Técnicas) - Instituto de Farmacología, Facultad de Medicina, Universidad de Buenos Aires, Argentina.
2 Sanatorio Julio Méndez
3 L' Oréal Pesquisa e Inovação - Episkin Brasil Biotecnologia, Rio de Janeiro, Brasil.
POSTER 263
Evaluating markers of oxidative stress and inflammation in RHE models exposed to combined UV radiation and pollution
Human Health – Replacement
Maria da Graça Landim Bravo 1, Isadora de Jesus da Silva 1, Nayara Fernanda Tokashike de Araújo 1, Gabriel Neves Cezarette 1, Ludmilla Tonani 1, Marcia Regina von Zeska 1, Rodrigo de Vecchi 2, Vanja Dakic 2, Lorena Rigo Gaspar Cordeiro 1
1 School of Pharmaceutical Sciences of Ribeirao Preto - University of Sao Paulo
2 L'Oréal Research and Innovation - Episkin Brasil Biotecnologia
POSTER 274
Transpacific Eye Hazard Journey: Reproducibility of the STE0.5 for surfactants
Human Health - Replacement
NATHALIE ALEPEE 1, TAKAYUKI ABO 2, MARIA LAURA GUTIERREZ 3, DAVE ALLEN 4, ALESSANDRA CAVARZAN 5, CHELSEA O'DRISCOLL 6, ANDREEA CUCIUREANU 4, KARSTEN R. MEWES 7, ELS ADRIAENS 8
1 L'Oreal
2 Kao Corporation
3 Laboratorio de Métodos Alternativos. CONICET - University of Buenos Aires
4 ICCS
5 Reckitt Benckiser Italia S.P.A
6 Procter & Gamble
7 Henkel AG & Co. KGaA
8 Adriaens Consulting BV
POSTER 304
Development of TTC values for inhalable substances
Human Health – Replacement
Anke Londenberg 1, A.M. Api 2, F. Boislève 3, AM Bowden 4, S Collins 5, Kaushal Joshi 2, H Moustakasb 2, J Muldoon 6, Grace Patlewicz 7, M Zocher 1, Madhuri Singal 8, Nikaeta Sadekar 2, Sylvia Escher 1
1 Fraunhofer ITEM
2 Research Institute for Fragrance Materials
3 Chanel
4 Unilever
5 Procter & Gamble, Cincinnati
6 Research Institute for Fragrance Materials, Mahwah
7 US EPA
8 L’Oréal
POSTER 225
U-SENS: A Game-Changer for Skin Sensitization Assessment Under OECD TG 497 Standards.
Human Health - Policy / Regulatory
NATHALIE ALEPEE 1, FLEUR TOURNEIX 1, LAURENT NARDELLI 1
1 L'Oreal R&I
POSTER 730
Launch of the DIM testing project: when animal testing is difficult, impossible and meaningless (DIM) and implications for REACH regulation
Regulatory Toxicology - Policy / Regulatory
Jay Ingram 1, Giorgia Pallocca 1, Martijn van Velthoven 2, Vincente Aranda 3, Anders Bergqvist 4, Maria Blanco-Rubio 5, Ben Carrick 6, Jay Dawick 7, Nicolas Fabre 8, Mojca Fuart-Gatnik 9, Rafael Gozalbes 3, Marlly Guarin 5, Steve Gutsell 10, Christina Hickey 11, Aleksandra Mostrag-Szlichtyng 9, Kyle Roush 12, Martijn Rooseboom 5, Marten Schults 13, Eva Serrano Candelas 3, Chantal Smulders 5, Paul Sterchele 13, Sagar Thakali 6, Paul Thomas 14, Xiaoling Zhang 12
1 Humane World for Animals
2 VelTox Strategy Consultancy
3 ProtoQSAR
4 GPC
5 Shell
6 Kenvue
7 Innospec
8 L’Oréal
9 Merck
10 Unilever
11 DSM Firmenich
12 P&G
13 IFF
14 Kreatis
Scientific Program:
August 31st
- 9:15 – 10 :00 Theoretical Foundations – The OECD 467 Framework Nathalie Alépee, L’Oréal R&I/Episkin
- 10:15- 12:40 Eye Irritation Using a Reconstructed Human Cornea Model (OECD TG 492B) – Vanja Dakic, Nathalie Alépee, L’Oréal R&I/Episkin
September 1st
- 9:30 - 11:00 Véronique POULSEN will chair a session: Global Harmonization in Risk Assessment: Navigating the Complexities of Animal Testing, Regulatory Divergence, and Environmental Sustainability
September 2nd
- 9:30 Gladys OUEDRAOGO will make an oral presentation in a session (75): Update to OECD Guidance Document 34 on the validation of test methods and Defined Approaches
- 11:30 - 13:00 Vanja DAKIC will talk in a session: Confidence in in vitro alternatives to animal testing - defining standards to ensure rigorous and reproducible data
- 11:30 - 13:00 Session Chair : David Allen - International Collaboration on Cosmetics Safety (ICCS) + Gladys OUEDRAOGO (L'Oréal R&I): The journey towards animal-free systemic toxicity assessment for cosmetics
- 14:30 - 16:00 Session Chair David Allen - ICCS & Nathalie Alépée - L'Oreal R&I Sailing the Seas of Validation: Challenges Encountered to Chart the Course Ahead
- 17:30 Vanja DAKIC and Nicolas FABRE will present on ICCS Ancillary Session – Building Confidence in NGRAs for Cosmetics
September 3rd
- 9:30 - 11:00 Vanja DAKIC will chair a session: The Future is Now The Power of NAMs for a global acceptance for Local Tolerance
- 11:30 - 13:00 Session Chair Veronique Poulsen - L'Oréal & Amelie Ott - ICCS: Environmental safety assessment of chemicals– Progress of different animal-free tools, similarities and differences with human safety assessments
- 9:30 Gladys OUEDRAOGO will co-chair and make an oral presentation in a session (113): Overcoming barriers to regulatory uptake of Next Generation Risk Assessment
- 11:30 - 13:00 Nicolas FABRE will co-chair a session with Kristie Sullivan - Institute for In Vitro Sciences: From internal decision making to regulatory approval: Finding strategies to accelerate the use of NAMs
Join us at WC13!
