NAME: EpiSkinTM / Reconstructed Human Epidermis
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             EpiSkin is an in vitro reconstructed human epidermis from normal human keratinocytes cultured on a collagen matrix at the air-liquid interface. This model is histologically similar to the in vivo human epidermis. 
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            SPECIFIC MARKERS
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            APPLICATIONS 
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            Different markers: 
            
                - Filaggrin
 
                - Involucrin
 
                - Loricrin
 
                - Keratin 10
 
                - Keratin 5
 
                - Presence of different epidermal classes of lipids comprising ceramides
 
             
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            Skin Irritation
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            Skin Corrosion | 
        
        
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            Phototoxicity | 
        
        
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            DNA damage | 
        
        
            Dermal-Epidermal junction markers 
            
                - Type IV collagen
 
                - Laminin V
 
                - Alpha6Beta4-integrin
 
                - BP antigen
 
             
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            Bacterial adhesion | 
        
        
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            Omics | 
        
        
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             Proliferation markers 
            
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            Permeability | 
        
        
            
            FORMAT
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                - 0.38 cm² (EpiSkinTM Small Model)
 
                - 1.07 cm² (EpiSkin TM Large Model)
 
             
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