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The EpiSkinTM model is adapted to the evaluation of products in several applications such as:

Safety assays:

• In vitro Skin Corrosion (under OECD TG 431 guidelines)
• In vitro Skin irritation (under OECD TG 439 guidelines)
• Acute and chronic skin irritation for topical formulations
• Phototoxicity testing of raw materials or finished products

Efficacy assays:

• Percutaneous absorption
• Effects of UVA and UVB exposure/ UVB protection
• Genotoxicity (micronucleus test & COMET assay) for topically applied compounds or formulations
• Bacterial adhesion for screening antibiotics
• Genomic and transcriptomic signatures
• Pharmacology /Toxicology
• Colorimetric response to skin dyes