Bibliography: Scientific References and posters

APPLICATIONS : SKIN IRRITATION OF CHEMICALS

Expression of skin-derived antileukoproteinase (SKALP) in reconstructed human epidermis and its value as a marker for skin irritation

1998 Acta Derm Venereol 1998 Mar ;78(2):107-113 | Department of Dermatology, Leiden University Medical Center, The Netherlands

AUTHORS : Boelsma E. Junginger HE Ponec M Tanojo H

In vivo human skin barrier modulation by topical application of fatty acids

1998 Skin Pharmacol Appl Skin Physiol 1998 Mar ;11(2):87-97 | Division Pharmaceutical Technology, Leiden/Amsterdam Center for Drug Research, Leiden University, The Netherlands

AUTHORS : Boelsma E. Egelrud T Forslind B Kempenaar JA Koerten HK Mommaas AM Pallon J Ponec M Vicanova J

Normalization of epidermal calcium distribution profile in reconstructed human epidermis is related to improvement of terminal differentiation and stratum corneum barrier formation

1998 J Invest Dermatol 1998 Jul ;111(1):97-106 | Department of Dermatology, Leiden, The Netherlands

AUTHORS : Gibbs S Kempenaar J Mommaas A M Mulder A Ponec M Weerheim A

Epidermal growth factor and temperature regulate keratinocyte differentiation

1997 Arch Dermatol Res 1997 ;289 (6):317-26 | Department of Dermatology, Leiden University Hospital, The Netherlands.

AUTHORS : Gooris G S Kempenaar J Mommaas A M Mulder A Ponec M Weerheim A

The formation of competent barrier lipids in reconstructed human epidermis requires the presence of vitamin C

1997 J Invest Dermatol 1997 Sep ;109 (3):348-55 | Department of Dermatology, Leiden University Medical Center, The Netherlands.

AUTHORS : Gibbs S Kempenaar J Ponec M Valstar D Vicanova J

Culture of reconstructed epidermis in a defined medium at 33 degrees C shows a delayed epidermal maturation, prolonged lifespan and improved stratum corneum

1997 Arch Dermatol Res 1997 Sep ;289 (10):585-95 | Department of Dermatology, Leiden University Medical Centre, The Netherlands.

AUTHORS : Bodde H. E. Boelsma E. Ponec M Tanojo H

An in vivo-in vitro study of the use of a human skin equivalent for irritancy screening of fatty acids

1997 Journal of investigative dermatology 1997 ;11 (4):365-376 | Department of Dermatology, Leiden University Hospital, Leiden, Netherlands; Leiden/Amsterdam Center for Drug Research, Division of Pharmaceutical Technology, Leiden University, Leiden, Netherlands

AUTHORS : Bodde H. E. Boelsma E. Ponec M Tanojo H

APPLICATIONS : SKIN IRRITATION OF CHEMICALS

Assessment of the potential irritancy of oleic acid on human skin: Evaluation in vitro and in vivo

1996 Toxicology in Vitro 1996 ;10 (6):729-742 | M. Ponec, Department of Dermatology, Leiden University Hospital, PO Box 9600, 2300 RC Leiden

AUTHORS : Koerten H K Mommaas A M Mulder A A Ponec M Vicanova J

Impaired desquamation in the in vitro reconstructed human epidermis

1996 Cell Tissue Res 1996 Oct ;286 (1):115-22 | Department of Dermatology, Bld. 1-P4Q, Leiden University Hospital, P. O. Box 9600, 2300 RC Leiden, The Netherlands.

AUTHORS : Bouwstra J A Gooris G S Kempenaar J Ponec M Weerheim A

Characterization of stratum corneum structure in reconstructed epidermis by X-ray diffraction

1995 J Lipid Res 1995 ;36 (3):496-504 | Leiden/Amsterdam Center for Drug Research, Leiden University, The Netherlands.

AUTHORS : Fartasch M Huner A Ponec M von den Driesch P

APPLICATIONS : SKIN IRRITATION OF CHEMICALS

Expression of integrin receptors and ICAM-1 on keratinocytes in vivo and in an in vitro reconstructed epidermis: effect of sodium dodecyl sulphate

1995 Arch Dermatol Res 1995 ;287 (3-4):249-53 | Department of Dermatology, University of Erlangen-Nurnberg, Germany.

AUTHORS : de Lannoy L Jansen H Kalkman I Kempenaar J Ponec M Weerheim A

Triglyceride metabolism in human keratinocytes cultured at the air-liquid interface

1995 Arch Dermatol Res 1995 ;287 (8):723-30 | Department of Dermatology, University Hospital Leiden, The Netherlands.

AUTHORS : Kempenaar J Ponec M

APPLICATIONS : SKIN IRRITATION OF CHEMICALS

Use of human skin recombinants as an in vitro model for testing the irritation potential of cutaneous irritants

1995 Skin Pharmacol 1995 ;8 (1-2):49-59 | Department of Dermatology, University Hospital Leiden, The Netherlands.

AUTHORS : Bialik W. Bodde H. E. Hoogstraate A J Kempenaar J A Ponec M Schrijvers A H Simonetti O

APPLICATIONS : PERCUTANEOUS ABSORPTION

Visualization of diffusion pathways across the stratum corneum of native and in-vitro-reconstructed epidermis by confocal laser scanning microscopy

1995 Arch Dermatol Res 1995 ;287 (5):465-73 | Department of Dermatology, University Hospital, Leiden, The Netherlands.

AUTHORS : Fartasch M Ponec M

Improved barrier structure formation in air-exposed human keratinocyte culture systems

1994 J Invest Dermatol 1994 ;102 (3):366-74 | Department of Dermatology, University of Erlangen, Germany.

AUTHORS : Fartasch M Ponec M

Improved barrier structure formation in air-exposed human keratinocyte culture systems

1994 J Invest Dermatol 1994 Mar ;102(3):366-374 | Department of Dermatology, University of Erlangen, Germany

AUTHORS : Demarchez M Higounenc I Ponec M Regnier M Schmidt R Shroot B

Improvement of epidermal differentiation and barrier function in reconstructed human skin after grafting onto athymic nude mice

1994 Arch Dermatol Res 1994 ;286(2):107-114 | Center International de Recherches Dermatologiques Galderma, Valbonne, France

AUTHORS : Hewitt S D Kempenaar J Noz K Ponec M Thody A J Todd C

APPLICATIONS : PHOTOPROTECTION

Co-culture of human melanocytes and keratinocytes in a skin equivalent model: effect of ultraviolet radiation

1993 Arch Dermatol Res 1993 ;285 (8):455-9 | Department of Dermatology, University of Newcastle upon Tyne, UK.

AUTHORS : Mommaas M Ponec M Tada J

Distribution of low-density lipoprotein receptors and apolipoprotein B on normal and on reconstructed human epidermis

1991 J Dermatol Sci 1991 ;2 (2):97-105 | Department of Dermatology, University Hospital Leiden, The Netherlands.

AUTHORS : Bodde H. E. Burger A Kempenaar J Ponec M Wauben Penris P J

Nitroglycerin and sucrose permeability as quality markers for reconstructed human epidermis

1990 Skin Pharmacol 1990 ;3 (2):126-35 | Department of Dermatology, University Hospital Leiden, The Netherlands.